一般社団法人
日本細胞生物学会Japan Society for Cell Biology

森和俊先生 ラスカー賞(基礎医学部門)受賞

一般社団法人 日本細胞生物学会
会長 貝淵 弘三

本学会員でありCSFのassociate editorを務められ、細胞生物学会に長年貢献されてきた京都大学森和俊教授が「米国のノーベル賞」と呼ばれるラスカー賞の基礎医学部門の受賞者に選ばれました。Unfolded Protein Response(UPR)、即ち小胞体ストレス応答の分子的基盤を明らかにした先駆的な研究で米国のPeter Walter 教授との共同受賞です。
まことにおめでとうございます。
森先生のご研究の益々のご発展をお祈りいたします。また、CSFへの森研究室からの最近の投稿論文として以下の論文がありますので、興味のある方は是非参照してください。


The Antipsychotic Olanzapine Induces Apoptosis in Insulin-secreting Pancreatic β Cells by Blocking PERK-mediated Translational Attenuation
Riwa Ozasa, Tetsuya Okada, Satomi Nadanaka, Takahiko Nagamine, Alisha Zyryanova, Heather Harding, David Ron, Kazutoshi Mori
Cell Structure and Function 38: 183-195

Vertebrate Unfolded Protein Response: Mammalian Signaling Pathways Are Conserved in Medaka Fish
Tokiro Ishikawa, Yoshihito Taniguchi, Tetsuya Okada, Shunichi Takeda, Kazutoshi Mori
Cell Structure and Function 36: 247-259

SEL1L Is Required for Endoplasmic Reticulum-associated Degradation of Misfolded Luminal Proteins but not Transmembrane Proteins in Chicken DT40 Cell Line
Satoshi Ninagawa, Tetsuya Okada, Shunichi Takeda, Kazutoshi Mori
Cell Structure and Function 36: 187-195

Luminal Domain of ATF6 Alone Is Sufficient for Sensing Endoplasmic Reticulum Stress and Subsequent Transport to the Golgi Apparatus
Yoshimi Sato, Satomi Nadanaka, Tetsuya Okada, Katsuya Okawa, Kazutoshi Mori
Cell Structure and Function 36: 35-47

pXBP1(U), a Negative Regulator of the Unfolded Protein Response Activator pXBP1(S), Targets ATF6 but not ATF4 in Proteasome-mediated Degradation
Hiderou Yoshida, Aya Uemura, Kazutoshi Mori
Cell Structure and Function 34: 1-10
第14回(2009年度)論文賞(CSF Award)授賞論文

ATF6 Is a Transcription Factor Specializing in the Regulation of Quality Control Proteins in the Endoplasmic Reticulum
Yusuke Adachi, Keisuke Yamamoto, Tetsuya Okada, Hiderou Yoshida, Akihiro Harada, Kazutoshi Mori
Cell Structure and Function 33: 75-89

Reduction of Disulfide Bridges in the Lumenal Domain of ATF6 in Response to Glucose Starvation
Satomi Nadanaka, Hiderou Yoshida, Kazutoshi Mori
Cell Structure and Function 31: 127-134

XBP1 is Critical to Protect Cells from Endoplasmic Reticulum Stress: Evidence from Site-2 Protease-deficient Chinese Hamster Ovary Cells
Hiderou Yoshida, Satomi Nadanaka, Ryuichiro Sato, Kazutoshi Mori
Cell Structure and Function 31: 117-125

Analysis of ATF6 Activation in Site-2 Protease-deficient Chinese Hamster Ovary Cells
Satomi Nadanaka, Hiderou Yoshida, Ryuichiro Sato, Kazutoshi Mori
Cell Structure and Function 31: 109-116

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